5 Quality Liver Health Supplements – How To Choose & What To Look For

The liver is the largest organ in the human body. It weighs approximately 2–3% of the average body weight. It is located in the upper right quadrant of the abdomen, above the stomach. (Sources 1,9) The liver plays a vital role in digestion, metabolism, detoxification, and immunity. (Sources 3,5,7)

Avoiding harmful foods, maintaining a healthy weight, exercising regularly, and having a balanced diet are necessary for a healthy liver. (Sources 8,9)

The popularity of liver health supplements has led to hundreds of brands flooding the marketplace; however not all supplements are created equal! We examine a number of different factors:

Essential Ingredients
Label Accuracy
Potential Results
Product Safety
Consumer Reviews & Feedback
Refund & Return Policy

Warning: we advise consumers to follow label directions and use as directed by the manufacturers. The recommended dose should not be exceeded.

Has your brand been third-party tested?

You should never buy supplements that don’t have Certificate of Analysis. The studies should be conducted in labs that are not affiliated with the manufacturer. These labs verify the product for safety and potency.

Does your supplement contain cheap synthetic fillers?

Some brands add artificial fillers to cut cost to offer cheap products. Some of these cheap fillers we found were additives and artificial coloring. You should never purchase cheap products when it comes to supplements.

No return policy or customer service

A reputable supplement company will offer 100% money-back guarantee policy and provide customer support through phone number and email. We noticed many formulas out there are just copies of the top-rated brands. They don’t offer an easy refund policy or don’t even have a phone number to prove they are real.

Avoid Subscription Auto-Billing Offers – unfortunately many brands use this trick to charge your card without your authorization, even if a customer returns the product. One trick is they charge your card even 6 months after you made your initial purchases, which most people forgot about it. If you’re happy with the service, then it’s best to make another purchase in the future.

The result: we purchased and reviewed 127+ supplements in the market and compiled a list of our 5 picks based on their ingredients, label accuracy, pricing, return policy, and overall customer satisfaction.*

5 Quality Liver Health Supplements

1. PureNature Liver Health [1]

PureNature has been in the market for a long time and is one of the most reputable companies. One of the few companies that offer 24/7 customer support through phone and email; they also offer a 1-year full refund policy which is unmatched in the market.

PureNature Liver Health contains all the recommended ingredients including Zinc, Milk Thistle (also known as Silymarin), Dandelion, and Artichoke Extract and many more.

Pros: contains the essential ingredients, manufactured in the USA, lab tested for potency, 1-year full refund policy

Cons: sometimes out of stock due to demand

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*Individual Results May Vary. We encourage consumers to research by visiting each product websites for more information.

2. Thorne Liver

Thorne is another reputable company. This formula contains Milk Thistle, Burdock, Berberine and more, Although it’s missing some of our essential ingredients it’s still a great choice.

Pros: manufactured in the USA, Milk Thistle, Burdock, Berberine, lab tested for potency and label accuracy

Cons: short return policy of only 60 days, missing some of the essential ingredients

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*We earn a commission if you click on this link to make a purchase. We encourage consumers to research by visiting each product websites for more information.

3. Gaia Liver Health

Gaia Herbs Liver Health contains Milk Thistle, Turmeric and some other ingredients, in phyto-caps. It’s a great option for many consumers. Gaia Herbs lists the amount of each ingredient they use in the product.

Pros: manufactured in the USA, contains some of the essential ingredients

lab tested for potency and label accuracy

Cons: short return policy of only 45 days

missing some of the essential ingredients

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*We earn a commission if you click on this link to make a purchase. We encourage consumers to research by visiting each product websites for more information.

4. Pure Encapsulations Selenium

Pure Encapsulations is a top rated company with many years of track record. This formula contains Silymarin milk thistle as the main ingredient, suitable for people who are looking for a single ingredient formula; manufactured in the USA.

Pros: contains milk thistle, manufactured in the US

lab tested for label accuracy

Cons: limited 30 days return policy

only one ingredient

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*We earn a commission if you click on this link to make a purchase. We encourage consumers to research by visiting each product websites for more information.

5. Nature’s Bounty Milk Thistle

Nature’s Bounty is another well-known company. Their milk thistle formula is a top rated supplement popular among consumers. This supplement contains 250mg of milk thistle per serving; manufactured in USA.

Pros: contains milk thistle, manufactured in the USA

lab tested for potency and label accuracy

Cons: 60 days return policy

only contains one main ingredient

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*We earn a commission if you click on this link to make a purchase. We encourage consumers to research by visiting each product websites for more information.

Contact Us:

If you have any questions please don’t hesitate to contact us. We would love to review different brands and feature more top formulas. We are open to any recommendations on how to make our site experience better. The more brands and formulas we review, the better we can serve you.

Unfortunately, some brands don’t like to be reviewed or featured; they use scare tactics and legal notices to be removed from our database.

contact@supplementslab.org

If you’re a brand owner and wish to be removed from our database, contact us using the email address above.

Sources & Citations

1. Z. Abdel-Misih, S. R., & Bloomston, M. (n.d.). Liver Anatomy.PubMed Central (PMC). https://doi.org/10.1016/j.suc.2010.04.017

2. Kalra, A., Yetiskul, E., Wehrle, C. J., & Tuma, F. (2023, May 1). Physiology,Liver – StatPearls – NCBI Bookshelf. Physiology, Liver – StatPearls – NCBIBookshelf. https://www.ncbi.nlm.nih.gov/books/NBK535438/

3. … Liver. (2021, September 28). NIH News in Health. https://newsinhealth.nih.gov/2021/10/fighting-fatty-liver

4. Responses in the Liver – PubMed. (2018, April 26). PubMed. https://doi.org/10.1146/annurev-immunol-051116-052415

5. Your Liver Delivers. (2017, May 16). NIH News in Health. https://newsinhealth.nih.gov/2014/03/your-liver-delivers

6. An Updated Phytopharmacological Review on Medicinal Plant of Arab Region: Apium graveolens Linn – PubMed. (2017, June 1). PubMed. https://doi.org/10.4103/phrev.phrev_35_16

7. Trimble, L. (2018, January). Accessibility at JSTOR: From box-checking to a more inclusive and sustainable future. Learned Publishing, 31(1),21–24. https://doi.org/10.1002/leap.1134

8. The potential benefits of red beetroot supplementation in …. – PubMed.(2015, April 14). PubMed. https://doi.org/10.3390/nu7042801

9. Milk thistle (Silybum marianum): A concise overview on its …. uses inliver … – PubMed. (2018, November 1). PubMed. https://doi.org/10.1002/ptr.6171

1. PureNature Liver Health [1]

PureNature Liver Health contains all the recommended ingredients including Zinc, Milk Thistle (also known as Silymarin), Dandelion, and Artichoke Extract and many more.

Pros: contains the essential ingredients, manufactured in the USA, lab tested for potency, 1-year full refund policy

Cons: sometimes out of stock due to demand

Learn More

*Individual Results May Vary. We encourage consumers to research by visiting each product websites for more information.